Mechanism Initiating Ventricular Fibrillation Demonstrated in Cultured Ventricular Muscle Tissue
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منابع مشابه
Mechanism initiating ventricular fibrillation demonstrated in cultured ventricular muscle tissue.
Ventricular muscle strips of the rat embryo heart were used for tissue culture preparations without adding trypsin. Fibrillation-like arrhythmia was induced by adding aconitine or strophanthin, and the potentials were recorded with one or two microelectrodes. The tracing by one microelectrode was no different than tracings from fibrillating adult mammalian hearts. The size and shape of the acti...
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The cellular events during the initiation and maintenance of ventricular fibrillation (VF) are poorly understood. We developed a nonischemic, isolated, perfused rabbit Langendorff preparation in which sustained VF could be induced by alternating current (AC) and which allowed changes in perfusate composition. We also used Na+-K+ pump inhibition (10 ,uM ouabain or K'-free perfusate) to induce VF...
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The reentrant wave fronts in ventricular fibrillation (VF) have only a limited life span. The mechanisms by which these reentrant wave fronts terminate are unknown. We performed computerized mapping studies in six open-chest dogs before and after right ventricular subendocardial ablation with Lugol's solution. Recordings were made with 56 bipolar electrodes separated by 3 mm. Baseline pacing wa...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1970
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.26.2.201